Open AccessIntestinal epithelial dysplasia
Author(s) -
Т. Е. Таранушенко,
Е. М. Васильева,
Е. В. Анциферова,
Л. Н. Карпова,
Ю. С. Шамова
Publication year - 2020
Publication title -
tihookeanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
ISSN - 1609-1175
DOI - 10.34215/1609-1175-2020-1-91-94
Subject(s) - enteropathy , microvillus , dysplasia , pathology , medicine , polyhydramnios , disease , gastroenterology , fetus , biology , pregnancy , membrane , genetics
The article presents a clinical case of intestinal epithelial dysplasia (tufting enteropathy), a rare disease which relates to congenital diarrheas, has a particular clinical presentation and is life-threating. The diagnosis was confirmed by histological examination and electronic microscopy of mucous membrane of small intestine. Additional evidence is substantiated for the existence of prenatal markers of intestinal epithelial dysplasia represented as polyhydramnios and intrauterine dilatation of fetal intestinal loops. These symptoms are considered to be a clinical hallmark of sodium and chloride diarrheas and are described in single cases in enteropathy called a microvillus inclusion disease.