Open AccessClinical efficacy of the affinity purified antibodies to the protein S100 in the complex rehabilitation of the infants with acute obstructive bronchitis affected by perinatal pathology of central nervous system
Author(s) -
Yu. L. Mizernitsky,
И. М. Мельникова,
В. А. Павленко,
В Н Воловенко,
Н. М. Кондрашова
Publication year - 2019
Publication title -
tihookeanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
ISSN - 1609-1175
DOI - 10.34215/1609-1175-2019-4-42-46
Subject(s) - medicine , bronchitis , central nervous system , rehabilitation , autonomic nervous system , antibody , anesthesia , heart rate , immunology , physical therapy , blood pressure
Objective: The objective is to assess the clinical efficacy of the inclusion of release-active medication of affinity purified antibodies to protein S100 in complex rehabilitation of infants with old acute obstructive bronchitis affected by perinatal pathology of central nervous system of hypoxic genesis. Methods: 210 infants aged from 2–36 months, who suffered events of acute obstructive bronchitis, were examined. Along with clinical methods of examination, a computer bronchophonography and assessment of heart rate variability were performed. Results: Additional inclusion of release-active medication ‘Tenoten for children’ in the complex of rehabilitation of these patients had a positive effect on autonomic balance and autonomic component of bronchial obstruction. At the same time, the short course of Tenoten (1 month) did not prevent recurrent events of bronchial obstruction. Conclusions: Probably, patients with recurrent events of acute bronchial obstruction in combination with pronounced functional disorders of vegetative state require longer courses of release-active medication which normalized the activity of the central nervous system.