Open AccessBacteriophages: A Revisited Strategy for the Treatment of Severe Bacterial Infections
Author(s) -
R.J.S. Badaró
Publication year - 2020
Publication title -
journal of bioengineering and technology applied to health/journal of bioengineering and technology apllied for health
Language(s) - English
Resource type - Journals
eISSN - 2674-8568
pISSN - 2595-2137
DOI - 10.34178/jbth.v2i3.74
Subject(s) - phage therapy , microbiology and biotechnology , antibiotics , bacteria , virulence , antibiotic resistance , pathogen , biology , bacteriophage , virology , gene , escherichia coli , genetics
Bacteriophages are viruses that infect and parasitize bacteria. The current increase in the incidence of antibiotic resistance in human bacteria has favoredthe study of phages as a therapeutic alternative (phage therapy). Phage therapy is defined as the administration of virulent phages directly to a patient to lyse the bacterial pathogen that is causing a clinically severe infection. The ideal route of administration and modification of bacteriopaghes genetically to deactivate bacterial resistance genes is the next future to antibiotic recovery sensitivity of MDR organisms.