Open AccessSYNTHESIS AND INVESTIGATION OF BIOMIMETIC HYDROXYAPATITES DOPED BY SILICATE AND CARBONATE ANIONS IN THE PRESENCE OF CITRATE IONS
Author(s) -
M. Troubitsin,
Viet Hung Hoang,
Л. Фурда
Publication year - 2020
Publication title -
vestnik bgtu im. v.g. šuhova
Language(s) - English
Resource type - Journals
ISSN - 2071-7318
DOI - 10.34031/2071-7318-2020-5-3-106-113
Subject(s) - crystallinity , hydroxyapatites , scanning electron microscope , ion , agglomerate , materials science , carbonate , precipitation , solubility , crystallite , silicate , nuclear chemistry , oxalate , chemical engineering , chemistry , inorganic chemistry , crystallography , calcium , metallurgy , organic chemistry , physics , meteorology , engineering , composite material
In the present work, biomimetic hydroxyapatite (BHAP) doped with silicate and carbonate anions in the presence of citrate ions are synthesized by chemical precipitation from aqueous solutions. According to the results of X-ray phase analysis (XRD), all the obtained materials are single-phase. Scanning electron microscopy (SEM) demonstrates that BHAP powders are a collection of agglomerated particles with similar morphology. Dynamic light scattering confirms that the synthesized BHAPs consist of agglomerates 1–4μm in size. For all samples, with an increase in the number of introduced citrate ions, decreases in the average crystallite size and degree of crystallinity are observed. With an increase in the concentration of citrate ions, the content of agglomerate fractions of 1–2μm in size increases from 70.16 to 75.43%. The solubility of hydroxyapatite samples in physiological saline (ω(NaCl) = 0.9%) at temperatures of 22°C and 37°C is studied. It is revealed that for all synthesized BHAPs, the amount of released Ca2+ ions into the liquid phase increases. The maximum yield of Ca2+ ions in physiological saline is recorded in BHAP with the highest content of citrate ions. The obtained results allow to consider the synthesized BHAP as a promising medical biomaterial for the regeneration of bone tissue.