Open AccessSpecific characteristics of STEMI in COVID-19 patients and their practical implications
Author(s) -
Mauro Gitto,
Laura Novelli,
Bernhard Reimers,
Gianluigi Condorelli,
Giulio Stefanini
Publication year - 2022
Publication title -
kardiologia polska
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.527
H-Index - 34
eISSN - 1897-4279
pISSN - 0022-9032
DOI - 10.33963/kp.a2022.0072
Subject(s) - medicine , covid-19 , myocardial infarction , concomitant , intensive care medicine , pandemic , isolation (microbiology) , disease , cardiology , medical emergency , pathology , infectious disease (medical specialty) , bioinformatics , outbreak , biology
ST-elevation myocardial infarction (STEMI) is one of the cardiac emergencies whose management has been most challenged by the COVID-19 pandemic. Patients presenting with the "lethal combo" of STEMI and concomitant SARS-CoV-2 infection have faced dramatic issues related to the need for self-isolation, systemic inflammation with multi-organ disease and difficulties to obtain timely diagnosis and treatment. The interplay between these and other factors has partly neutralized the major advances in STEMI care achieved in the last decades, significantly impairing prognosis in these patients. In the present review article, we will provide an overview on mechanisms of myocardial injury, specific clinical and angiographic characteristics and contemporary management in different settings of STEMI patients with COVID-19, alongside the inherent implications in terms of in-hospital mortality and short-term clinical outcomes.