Efficacy and safety of the Amplatzer Duct Occluder II for ventricular septal defect closure: a meta-analysis

Transcatheter closure has become an effective and safe method to repair ventricular septal defects (VSDs). However, the devices used for VSD closure in the past frequently led to serious complications, such as complete atrioventricular block. The second‑generation device, the Amplatzer Duct Occluder (ADO II), was originally designed to block small‑ and medium‑sized patent ductus arteriosus. Interestingly, there are some reports of the use of the ADO II to close VSD because of less complications.