Open AccessNew methodological approaches for assessing thrombus formation in cardiovascular disease
Author(s) -
Kazuya Hosokawa,
Tomoko Ohnishi-Wada,
Tomoka Nagasato,
Hisayo Sameshima-Kaneko,
Chiaki Oyamada,
Jeffrey R. Dahlen
Publication year - 2020
Publication title -
kardiologia polska
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.527
H-Index - 34
eISSN - 1897-4279
pISSN - 0022-9032
DOI - 10.33963/kp.15493
Subject(s) - medicine , thrombus , disease , intensive care medicine , cardiology
Antiplatelet therapy is the mainstay preventive strategy for cardiovascular diseases, and dual antiplatelet therapy comprising aspirin and a P2Y12 inhibitor is the standard treatment for patients who underwent percutaneous coronary intervention. The Total Thrombus‑Formation Analysis System (T‑TAS) is a microchip flow‑chamber system developed to evaluate overall thrombus formation under flow conditions, which is reportedly able to assess single and combined antithrombotic therapy. Here, we focus on this new system, T‑TAS, and review its characteristics together with those of the conventional systems available for evaluation of antithrombotic therapies for cardiovascular diseases.