Open AccessRho GTPase‑activating protein 1 promotes apoptosis of myocardial cells in an ischemic cardiomyopathy model
Author(s) -
Xuezhi Zhang,
Jun Guan,
MingLei Guo,
Hongji Dai,
Shanglang Cai,
Chunxiao Zhou,
Yongbin Wang,
Qiaoji Qin
Publication year - 2019
Publication title -
kardiologia polska
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.527
H-Index - 34
eISSN - 1897-4279
pISSN - 0022-9032
DOI - 10.33963/kp.15040
Subject(s) - apoptosis , medicine , myocyte , ischemic cardiomyopathy , microbiology and biotechnology , gtpase , cardiomyopathy , cancer research , cardiac function curve , heart failure , biology , biochemistry , ejection fraction
Ischemic cardiomyopathy (ICM) leads to heart failure by causing apoptosis of cardiac myocytes. It is generally believed that a therapy targeting apoptosis of cardiac myocytes would improve the prognosis of patients with ischemic heart disease.