Open AccessAccelerating structure-based design of rapid uncharged reactivators of organophosphate-inhibited human acetylcholinesterase by joint X-ray/neutron mechanistic studies
Author(s) -
Andrey Kovalevsky,
Oksana Gerlits,
Lukáš Górecki,
Xiaotian Kong,
Xiaolin Cheng,
Donald K. Blumenthal,
Palmer Taylor,
Carlo Ballatore,
Zoran Radić
Publication year - 2020
Language(s) - English
Resource type - Conference proceedings
DOI - 10.3390/iocc_2020-08037
Subject(s) - paraoxon , chemistry , nerve agent , oxime , organophosphate , acetylcholinesterase , sarin , stereochemistry , computational chemistry , biochemistry , enzyme , pesticide , agronomy , biology