Open AccessNovel structural-related analogs of PFI-3 (SRAPs) that target the BRG1 catalytic subunit of the SWI/SNF complex increase the activity of temozolomide in glioblastoma cells
Author(s) -
Lawrence M. Pfeffer,
YuYing He,
Chuanhe Yang,
Yinan Wang,
Joshua R. Sacher,
Michelle Sims,
D Jay Miller
Publication year - 2021
Publication title -
proceedings of 7th international electronic conference on medicinal chemistry
Language(s) - English
Resource type - Conference proceedings
DOI - 10.3390/ecmc2021-11610
Subject(s) - temozolomide , cancer research , smarcb1 , in vitro , in vivo , dacarbazine , medicine , chemistry , melanoma , protein subunit , glioblastoma , pharmacology , chromatin remodeling , biology , chromatin , dna , biochemistry , genetics , gene