Open AccessBiological evaluation of 4,5,7-trisubstituted Indeno[1,2-<em>b</em>]indoles reveals a potent inhibitor of protein kinase CK2 in tumor cells with diverse anti-cancer effects and preferential cytoplasmic localization
Author(s) -
Ehab ElAwaad,
Robin Birus,
Laurens Ballentin,
Faten Alchab,
Dagmar Aichele,
Laurent Ettouati,
Claudia Götz,
Marc Le Borgne,
Joachim Jose
Publication year - 2021
Publication title -
proceedings of 7th international electronic conference on medicinal chemistry
Language(s) - English
Resource type - Conference proceedings
DOI - 10.3390/ecmc2021-11450
Subject(s) - intracellular , kinase , ic50 , protein kinase a , cancer cell , in vitro , chemistry , apoptosis , serine , biochemistry , indole test , intracellular ph , protein kinase inhibitor , phosphorylation , biology , microbiology and biotechnology , cancer , genetics