Open AccessFormulation and investigation of turmeric extract and sodium benzoate loaded capsules
Author(s) -
Ildikó Bácskay,
Dávid Sinka,
Liza Józsa,
Gábor Vasas,
Zoltán Ujhelyi,
Pálma Fehér,
Béla Juhász,
Zoltán Szilvássy
Publication year - 2021
Publication title -
acta pharmaceutica hungarica
Language(s) - English
Resource type - Journals
eISSN - 1587-1495
pISSN - 0001-6659
DOI - 10.33892/aph.2021.91.11-20
Subject(s) - curcuminoid , curcuma , sodium benzoate , curcumin , capsule , active ingredient , traditional medicine , ingredient , solubility , chemistry , food science , mathematics , pharmacology , organic chemistry , medicine , biochemistry , biology , botany
Turmeric has been studied and used as a plant derivate active ingredient for centuries. Several effects of turmeric have been described, however the poor solubility of its active ingredients during the formulation development may limit oral applicability. The aim of research was to involve the development of a dietary supplement of a hard capsule containing turmeric (Curcuma longa) (ground powder from the root standardized to curcuminoid content) and sodium benzoate. The manufacturing technology and the analytic method of the formulation have been developed. Formulation studies according to the Ph. Hg. VIII. standards have been performed. The product may have insulin sensitizing and memory enhancing effects, related animal studies are ongoing.