Ultrasound-Responsive Materials for Drug/Gene Delivery | Zendy

Xiaowen Cai | Zendy; Yuan Jiang | Zendy; Mei Lin | Zendy; Jiyong Zhang | Zendy; Huanhuan Guo | Zendy; Fanwen Yang | Zendy; Albert Wingnang Leung | Zendy; Chuanshan Xu | Zendy

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Ultrasound-Responsive Materials for Drug/Gene Delivery

Author(s) -

Xiaowen Cai,

Yuan Jiang,

Mei Lin,

Jiyong Zhang,

Huanhuan Guo,

Fanwen Yang,

Albert Wingnang Leung,

Chuanshan Xu

Publication year - 2020

Publication title -

frontiers in pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.384

H-Index - 86

ISSN - 1663-9812

DOI - 10.3389/fphar.2019.01650

Subject(s) - drug delivery , drug , medicine , ultrasound , pharmacology , biomedical engineering , nanotechnology , materials science , radiology

Ultrasound is one of the most commonly used methods in the diagnosis and therapy of diseases due to its safety, deep penetration into tissue, and non-invasive nature. In the drug/gene delivery systems, ultrasound shows many advantages in terms of site-specific delivery and spatial release control of drugs/genes and attracts increasing attention. Microbubbles are the most well-known ultrasound-responsive delivery materials. Recently, nanobubbles, droplets, micelles, and nanoliposomes have been developed as novel carriers in this field. Herein, we review advances of novel ultrasound-responsive materials (nanobubbles, droplets, micelles and nanoliposomes) and discuss the challenges of ultrasound-responsive materials in delivery systems to boost the development of ultrasound-responsive materials as delivery carriers.

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