Open AccessHydrophobic interactions between polymeric carrier and palmitic acid-conjugated siRNA improve PEGylated polyplex stability and enhance in vivo pharmacokinetics and pharmacodynamics
Author(s) -
Sarett Samantha,
Werfel Thomas,
Jackson Meredith,
Kavanaugh Taylor,
Hattaway Madison,
Todd D. Giorgio,
Duvall Craig
Publication year - 2016
Publication title -
frontiers in bioengineering and biotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.081
H-Index - 44
ISSN - 2296-4185
DOI - 10.3389/conf.fbioe.2016.01.01467
Subject(s) - in vivo , biodistribution , chemistry , biophysics , nanocarriers , pegylation , pharmacokinetics , small interfering rna , pharmacology , biochemistry , in vitro , drug delivery , transfection , organic chemistry , medicine , biology , microbiology and biotechnology , polyethylene glycol , gene