Open AccessBisphosphonates in clinical practice
Author(s) -
Bilal Ahmad Rather,
Sajad A. Bhat
Publication year - 2019
Publication title -
j med sci
Language(s) - English
Resource type - Journals
eISSN - 2582-063X
pISSN - 0972-110X
DOI - 10.33883/jms.v22i2.460
Subject(s) - medicine , malignancy , osteoporosis , bone resorption , bone disease , bisphosphonate , resorption
Bisphosphonates are analogues of pyrophosphate where P-C-P forms the core of molecule in place of P-O-P.They suppress resorption of bone while itself getting absorbed to hydroxyapetite of bone. These are classified into three generations according to modifications in side chain. Bisphosphonates are widely used for osteoporosis, hypercalcemia of malignancy, Paget's disease of bone etc.
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