Open AccessIncidence of hypercalcemia and thiazide associated hypercalcemia on an OPD basis biochemical evaluation
Author(s) -
Moomin Hussain Bhat,
Mosin Saleem Khan,
Shariq Rashid Masoodi,
Shuja Abass,
Javaid Rasool Bhat,
Peerzada Ovais Ahmad,
Bisma Rafiq Wangnoo,
Taief Ahmad Dar,
Bathsheeba Andrabi,
Syed Mudassar
Publication year - 2019
Publication title -
journal of medical sciences/journal of medical sciences (srinagar. online)
Language(s) - English
Resource type - Journals
eISSN - 2582-063X
pISSN - 0972-110X
DOI - 10.33883/jms.v22i1.436
Subject(s) - thiazide , medicine , incidence (geometry) , primary hyperparathyroidism , concomitant , prospective cohort study , outpatient clinic , hypokalemia , gastroenterology , diuretic , physics , optics
Background: Hypercalcemia is most of the times diagnosed on routine biochemical evaluation, and concomitant use of thiazide diuretics is common since this group of antihypertensives is frequently prescribed worldwide.
Objective: To determine the incidence of hypercalcemia as well as thiazide-induced hypercalcemia on an OPD basis
Methods: In a prospective hospital-based descriptive study, patients for routine evaluation, attending outpatient clinics.
Results: A total of 373 patients participated in the study, out of which 101(27.1%) were hypertensive. 30 of the 101 hypertensive patients were on thiazides. Hypercalcemia was present in total of 7 (1.9%) patients, primary hyperparathyroidism was seen in 4 patients, out of which 2 patients were on thiazides. 6.7% (2/30) of the patients on thiazides were having hypercalcemia as compared to 1.5% (5/343) patients, not on thiazides (p=0.044).
Conclusion: About every 50 patients evaluated, one patient has hypercalcemia with frequency of hypercalcemia being significantly higher among subjects receiving thiazides than those not receiving thiazide drugs.