Open AccessInflammatory parameters in elderly women with and without sarcopenic obesity
Author(s) -
Silvana Schwerz Funghetto,
Alessandro Oliveira Silva,
Maurílio Tiradentes Dutra,
Marina Morato Stival,
Yuri Gustavo Sousa Barbalho,
Mateus Medeiros Leite,
Márcio Rabelo Mota,
Luciano Ramos de Lima,
Izabel Cristina Rodrigues Silva
Publication year - 2020
Publication title -
multi-science journal
Language(s) - English
Resource type - Journals
ISSN - 2359-6902
DOI - 10.33837/msj.v3i3.1306
Subject(s) - sarcopenia , sarcopenic obesity , medicine , obesity , interleukin 6 , population , tumor necrosis factor alpha , proinflammatory cytokine , gastroenterology , inflammation , interleukin , endocrinology , cytokine , environmental health
The combination of increased fat mass with a decrease in muscle mass and strength in the elderly has been termed sarcopenic obesity (SO). In addition, augmented levels of inflammatory markers have been reported in subjects with SO. Two hundred-sixteen obese elderly women were included in this cross-sectional study. They underwent body composition analysis by DEXA to define the presence of SO. Volunteers were divided into two groups: SO (n= 83; 66.7 ± 5.6 years) and non-SO (n= 133; 67.6 ± 4.9 years) for the comparison of inflammatory cytokines. There were no significant differences between SO and non-SO groups in the blood concentrations of the inflammatory markers analyzed, e.g. interleukin-6 (0.82 ± 0.20 vs 0.83 ± 0.19 pg/ml; p=0.64), C-reactive protein (2.70 ± 1.55 vs 2.82 ± 1.66 pg/ml; p=0.71), tumor necrosis factor alpha (0.71 ± 0.08 vs 0.70 ± 0.08 pg/ml; p=0.42) and interferon-gamma (0.75 ± 0.14 vs 0.74 ± 0.08 pg/ml; p=0.47), respectively. Thus, in the studied population, inflammatory markers are not exacerbated by SO when compared to obesity without sarcopenia.