Open AccessEffect of NSAIDs on Muscle Adaptations to Resistance Training: A Brief Review
Author(s) -
A. Ummu Salamah,
Junchul Shin,
JoonYoung Park
Publication year - 2019
Publication title -
journal of public health issues and practices
Language(s) - English
Resource type - Journals
ISSN - 2581-7264
DOI - 10.33790/jphip1100132
Subject(s) - medicine , muscle hypertrophy , resistance training , delayed onset muscle soreness , skeletal muscle , eccentric exercise , limiting , eccentric , physical therapy , physical medicine and rehabilitation , muscle damage , mechanical engineering , physics , quantum mechanics , engineering
Non-steroidal anti-inflammatory drugs (NSAIDs) are popular amongst various populations to treat a myriad of ailments. One common use is to lessen delayed onset muscle soreness (DOMS) after intense exercise, generally prevalent in eccentric muscle contractions. To date, many studies have been conducted investigating the effects of NSAIDs on skeletal muscle hypertrophy and function. Existing literature reports very different results and conclusions with respect to the effects of these drugs on resistance training-induced adaptations in skeletal muscle. To best answer the question concerning NSAIDs and functional muscle hypertrophy, this review outlines literature and categorizes various factors which influence study outcomes. Although the literature examining the topic is conflicting, the results seem to vary heavily based on the subjects’ characteristics, dosages, and resistance training protocols. Specifically, the age can be a pivotal factor in determining the response seen from supplementing with NSAIDs. In conclusion, NSAIDs may be a smart approach to DOMS for older populations, while younger individuals may be limiting exercise-induced skeletal muscle adaptations.