Akurasi Indeks Singh Dibandingkan Dual Energy X-Ray Absorptiometry (DEXA) dalam Evaluasi Osteoporosis

Background: Osteoporosis is a metabolic bone disease that commonly occurs, characterized by decreased bone mass and prone to fracture. Breast carcinoma patients have a higher risk developing osteoporosis, due to a decrease in estrogen levels resulting from the e?ect of a given treatment, thus early detection of osteoporosis is needed.Objective: To compare the accuracy of the Singh Index with DEXA as the gold standard in the evaluation of osteoporosis in breast carcinoma patients with positive estrogen receptor.Materials and method: This is a diagnostic test, comparing the accuracy of the Singh Index on hip joints radiography with DEXA in the evaluation of osteoporosis in 35 breast carcinoma patients with positive estrogen receptors who have been getting therapy. All patients were examined by hip joints radiography and DEXA. The result of hip joints radiography are read double-blindedly by 3 observers.Results: Examination of Singh Index compared with DEXA by using limit values of osteoporosis of ? 3 on Singh Index and ? -2.5 SD on T-score DEXA achieves the best sensitivity on total hip but low positive predictive value, whereas with the limit values of osteoporosis of ? 4 on Singh Index and ? -1 SD on T-score DEXA achieves most excellent sensitivity and accuracy at the femoral collum showing low bone mineral density.Conclusion: Singh Index has a low diagnostic value in screening osteoporosis, but can be used to assess low bone mineral density in breast carcinoma patients with estrogen receptor positive, especially in areas that do not have DEXA equipment