Open AccessARE TUMORAL MARKERS PREDICTIVE FACTORS FOR MOLECULAR SUBTYPES IN BREAST CANCER?
Author(s) -
V.C. Munteanu,
Georgiana Radu,
Monica Mihaela Cîrstoiu
Publication year - 2019
Publication title -
journal of surgical sciences
Language(s) - English
Resource type - Journals
eISSN - 2457-5364
pISSN - 2360-3038
DOI - 10.33695/jss.v5i4.249
Subject(s) - breast cancer , oncology , medicine , molecular pathology , cancer , neoplasm , immunohistochemistry , pathology , gene , biology , biochemistry
Breast cancer kills more women annually than any other type of neoplasm. Even though he has shown a particular interest in the medical body since ancient times, the very heterogeneous nature of the tumors and their versatility have made it difficult to find a diagnostic and therapeutic consensus that fully characterizes this pathology and describes its evolution. Immunohistochemical methods manage to outline a gene-molecular profile depending on the biomarkers expressed by each tumor. Correlations between clinical aspects and molecular characteristics of tumors are of particular importance in the management of such a case. The study examined the impact of breast cancer molecular subtypes on therapeutic management for a group of 438 patients treated on the Oncology Department of the Bucharest University Emergency Hospital during 2007-2017.