Open AccessEffectiveness of isotretinoin monotherapy in treatment of severe acne
Author(s) -
Л. С. Круглова,
N. V. Gryazeva
Publication year - 2020
Publication title -
medicinskij alfavit
Language(s) - English
Resource type - Journals
eISSN - 2949-2807
pISSN - 2078-5631
DOI - 10.33667/2078-5631-2020-6-36-40
Subject(s) - acne , isotretinoin , medicine , dermatology , tolerability , acne scars , adverse effect
The main goal of this study was to assess the frequency of effectiveness and the tolerability of therapy in the treatment of severe acne with isotretinoin (Sotret) as monotherapy. In this study, 115 patients with severe acne were examined and treated: 107 (94.69 %) with papulo-pustular acne, 7 (6.19 %) with conglobate acne, and 1 (0.88 %) with keloid acne. Evaluation of the frequency of outcomes in the treatment of severe acne with isotretinoin Sotret was studied based on data obtained during a medical examination, which evaluated the dynamics of changes in the severity of acne according to the classification adopted by the American Academy of Dermatology (AAD, 1990) and based on data from the Assessment of Psychological and Social Effect of Acne (APSEA) Questionnaire.