Open AccessGenetic predisposition and resistance to certain infectious diseases. II. Sexually transmitted infections
Author(s) -
S. N. Scherbo,
Dmitry S. Shcherbo,
A. L. Tishchenko,
М. И. Савина,
Т. И. Туркина
Publication year - 2020
Publication title -
medicinskij alfavit
Language(s) - English
Resource type - Journals
eISSN - 2949-2807
pISSN - 2078-5631
DOI - 10.33667/2078-5631-2020-5-5-8
Subject(s) - genetic predisposition , biology , immunology , genetics , major histocompatibility complex , gene
The review addresses issues related to genetic predisposition and resistance to sexually transmitted infections (STI). Genetic factors largely determine the susceptibility of the body to various diseases, including infectious ones. The main influence is given to the genes of the main histocompatibility complex and toll-like receptors. Some STI and genetic polymorphisms responsible for resistance and susceptibility to infections and related clinical consequences are considered. Knowledge of molecular genetic biomarkers is necessary to identify risk groups, conduct predictive measures, in particular vaccination.