Open AccessPlacental insufficiency and fetal growth restriction: etiology, prevention, and treatment
Author(s) -
Н. И. Тапильская,
К. Н. Мельников,
Irina A. Kuznetsova,
Ruslan I. Glushakov
Publication year - 2020
Publication title -
medicinskij alfavit
Language(s) - English
Resource type - Journals
eISSN - 2949-2807
pISSN - 2078-5631
DOI - 10.33667/2078-5631-2020-4-6-10
Subject(s) - placental insufficiency , etiology , placenta , preeclampsia , pathological , pregnancy , fetus , pathogenesis , placenta diseases , fetal growth , medicine , intrauterine growth restriction , obstetrics , spiral artery , biology , pathology , genetics
The review presents modern aspects of the etiology of placental insufficiency (uteroplacental vascular insufficiency), fetal growth restriction and preeclampsia, which arises primarily due to deficient remodeling of the uterine spiral arteries supplying the placenta during early pregnancy. The embryonic, maternal and placental factors of the occurrence of placental insufficiency and placental-related pathology considered. The issues of prevention and treatment of placental insufficiency are considered taking into account the common pathogenesis of this pathological condition.