Open AccessCorrection of endothelial dysfunction in COVID 19
Author(s) -
Nataliya Teplova,
Д. В. Гришин
Publication year - 2020
Publication title -
medicinskij alfavit
Language(s) - English
Resource type - Journals
eISSN - 2949-2807
pISSN - 2078-5631
DOI - 10.33667/2078-5631-2020-22-56-59
Subject(s) - covid-19 , endothelium , endothelial dysfunction , medicine , inflammation , pathogenesis , coronavirus , immunology , intensive care medicine , bioinformatics , virology , cardiology , biology , disease , outbreak , infectious disease (medical specialty)
COVID‑19 is acute respiratory infection caused by the new coronavirus SARS-CoV‑2 (2019-nCoV). Until now, the pathogenesis of the virus has not been fully studied, but the global medical practice is dominated by the theory of systemic inflammation as the main damaging factor of viral infection. A special role is given to the study of the state of the endothelium. Understanding the molecular components underlying functional disorders and vascular damage, together with the ability of new laboratory technologies to determine the effect of endothelial damage on the entire body, provides a key to modern treatment strategies. Antihypertensive, antiplatelet drugs and statins are the drugs whose effect on the functional state of the endothelium has been studied most fully.