Open AccessTherapeutic drug monitoring in Davydovsky Hospital: using HPLC–MS/MS method in practical healthcare
Author(s) -
Т. А. Родина,
Е. С. Мельников
Publication year - 2020
Publication title -
medicinskij alfavit
Language(s) - English
Resource type - Journals
eISSN - 2949-2807
pISSN - 2078-5631
DOI - 10.33667/2078-5631-2019-4-35(410)-47-52
Subject(s) - therapeutic window , therapeutic drug monitoring , drug , bioanalysis , medicine , pharmacology , chromatography , chemistry
There was shown that therapeutic drug monitoring by liquid tandem mass spectrometry is essential not only for the drugs with a narrow therapeutic window but also for “simple” medicines like anti‑hypertension and anticoagulant drugs. The examples of choosing an individual therapy and adjusting the drug dosage to eliminate side effects were given. The cases of solving non‑standard situations that arise during bioanalytical studies were considered.