Open AccessEnzymes from carbohydrase group destroy biofilm matrix of gram-positive and gram-negative bacteria
Author(s) -
Ю М Романова,
А. В. Тутельян,
А. П. Синицын,
В. М. Писарев,
Н. В. Алексеева,
Н. И. Филипова,
Э. Р. Толордава,
О. А. Синицына,
О. В. Емшанов
Publication year - 2020
Publication title -
medicinskij alfavit
Language(s) - English
Resource type - Journals
eISSN - 2949-2807
pISSN - 2078-5631
DOI - 10.33667/2078-5631-2019-4-34(409)-40-45
Subject(s) - carbohydrase , biofilm , bacteria , gram negative bacteria , gram , microbiology and biotechnology , enzyme , gramian matrix , matrix (chemical analysis) , gram positive bacteria , biology , chemistry , biochemistry , escherichia coli , chromatography , eigenvalues and eigenvectors , genetics , physics , quantum mechanics , gene
The effect of enzymes carbohydrases exopolysaccharide matrix of biofilms formed by gram-positive and gram-negative bacteria on abiotic surfaces was studied. The ability of a mixture of carbohydrase enzymes (hydrolases and lyases) to completely destroy the matrix of biofilms formed by gram-positive and gram-negative bacteria causing health-associated infections has been confirmed. An optimal mixture of carbohydrases possesed high anti-biofilm activity even when employed in relatively small concentrations and at a brief exposure time.