Open AccessFeatures of methods of glomerular filtration rate estimation
Author(s) -
И. А. Волкова,
М. И. Савина
Publication year - 2019
Publication title -
medicinskij alfavit
Language(s) - English
Resource type - Journals
eISSN - 2949-2807
pISSN - 2078-5631
DOI - 10.33667/2078-5631-2019-3-22(397)-43-47
Subject(s) - renal function , creatinine , urology , kidney disease , filtration (mathematics) , kidney , medicine , chemistry , endocrinology , mathematics , statistics
A decrease in glomerular filtration rate (GFR) is an earlier sign of detection of chronic kidney diseases compared to an increase in urea and blood creatinine concentrations. It is impossible to measure the glomerular filtration rate directly. GFR is determined by calculating the concentration of blood creatinine or by measuring the clearance of endogenous creatinine. The work shows the influence of methods for the determination of creatinine on the results of the calculation of glomerular filtration rate and terms for the correct choice of method of measuring glomerular filtration rate in different clinical situations associated with chronic kidney disease.