Frequency and nature of complications associated with drug and electric cardioversion in patients with atrial fibrillation in hypertension in combination with extracardial comorbid pathology and adherence to treatment

Aim. To evaluate the complex of antiarrhythmic therapy and adherence to treatment on an outpatient basis in patients with atrial fibrillation in hypertension in combination with extracardiac diseases. Methods. In an observational cohort study, 308 men aged 45–60 years old were observed with atrial fibrillation and hypertension in combination with diabetes mellitus (n = 40), diffuse toxic goiter (n = 42), hypothyroidism (n = 59), abdominal obesity (n = 64) and chronic obstructive pulmonary disease (n = 47). The comparison group consisted of 56 patients without extracardiac pathology. The work evaluated clinical, anthropometric data, the results of daily monitoring of ECG and echocardiography. Adherence to therapy was evaluated using a specialized Moriski-Green questionnaire. Results. Patients with diabetes mellitus on the background of electric cardioversion significantly more often developed CHF (p = 0.003), cardioembolism (p < 0.001), hospitalization (p = 0.040) and progression of AF (p < 0.050), relative to the comparison group. The number of regospitalizations was noted less after electrical cardioversion compared with only medical one. The adherence to drug therapy in patients with atrial fibrillation in hypertension with extracardiac disease was 26.7 %. Conclusion. The reasons for the lack of patient adherence to treatment require an integrated approach to its early resolution.