Open AccessBiological rhythm disturbances in depression
Author(s) -
М. Г. Полуэктов,
P. M. Khadzhaeva
Publication year - 2019
Publication title -
medicinskij alfavit
Language(s) - English
Resource type - Journals
eISSN - 2949-2807
pISSN - 2078-5631
DOI - 10.33667/2078-5631-2019-2-19(394)-5-10
Subject(s) - circadian rhythm , depression (economics) , melatonin , rhythm , chronobiology , neuroscience , dark therapy , psychology , hypothalamus , major depressive disorder , psychiatry , medicine , cognition , economics , macroeconomics
Depression belongs to the diseases with pronounced medical and social consequences, which include disability, reduced social functioning and suicides. There is the evidence that the depressive manifestations are closely related to disorders of circadian periodism and the function of the suprachiasmatic nuclei of the hypothalamus, the leading driver of biological rhythms. Authors reviewed the possibility to apply the concept of biological rhythms to the development and clinical features of depressive disorder. The potential effects of chronobiotic drugs like melatonin agonists is discussed.