Open AccessMediastinal Lymphadenopathy in Non-small Cell Lung Cancer: Prognostic Value of PET/CT
Author(s) -
Н.А. Огнерубов,
Tatiana S. Antipova
Publication year - 2019
Publication title -
medicinskij alfavit
Language(s) - English
Resource type - Journals
eISSN - 2949-2807
pISSN - 2078-5631
DOI - 10.33667/2078-5631-2019-2-17(392)-23-26
Subject(s) - medicine , standardized uptake value , lung cancer , positron emission tomography , malignancy , radiology , mediastinal lymph node , stage (stratigraphy) , lymph node , pet ct , nuclear medicine , cancer , pathology , metastasis , paleontology , biology
Positron emission tomography combined with computer tomography (PET/CT) is considered as a noninvasive method for evaluation in lung cancer. SUVmax provides information on biological aggressiveness, key pathological features and potential of tumor spread. However, standardized and generally accepted criteria for determining malignant and benign lymph nodes do not exist, which is a common problem for molecular diagnostics physicians and generates clinical demand, since the standardization of these criteria has the potential to improve diagnostic accuracy, comparability between research and a general understanding by clinicians. To this end, we tried to determine the diagnostic accuracy of the maximum standardized absorption value (SUVmax) for mediastinal lymph nodes, compare the ability to predict mediastinal malignancy: SUVmax, the ratio of SUVmax l node to SUVmax of the primary tumor (SUVmaxN/SUVmaxT), and also SUVmaxN/SUVmaxT multiplied by maximum tumor diameter (SUV index).