Open AccessBiomodeling of pulmonary pathologies by means of intratracheal instillation of sensitizing substances in laboratory animals
Author(s) -
L. A. Taboyakova,
О. В. Алимкина,
Н. С. Огнева,
Е. С. Савченко
Publication year - 2021
Publication title -
biomedicina
Language(s) - English
Resource type - Journals
eISSN - 2713-0428
pISSN - 2074-5982
DOI - 10.33647/2713-0428-17-3e-95-98
Subject(s) - intratracheal instillation , pneumonia , medicine , covid-19 , lung , pathology , pharmacology , bronchoalveolar lavage , disease , infectious disease (medical specialty)
A method for endotracheal administration was studied and optimized for the tasks of the Scientific Centre for Biomedical Technologies (SCBMT), Russia, on small and large laboratory animals. By means of intratracheal instillation of sensitizing substances, a biomodel of coronavirus pneumonia was created and tested in preclinical studies.