Open AccessStructural and functional properties of thermolable bacteriocin produced by the Limosilactobacillus fermentum IIE MD-150 strain
Author(s) -
А. В. Мачулин,
Igor V. Kosarev,
Т. Н. Абашина,
Vyacheslav M. Abramov,
Vladimir N. Uversky,
Andrey V. Karlyshev
Publication year - 2021
Publication title -
biomedicina
Language(s) - English
Resource type - Journals
eISSN - 2713-0428
pISSN - 2074-5982
DOI - 10.33647/2713-0428-17-3e-114-117
Subject(s) - lactobacillus fermentum , bacteriocin , strain (injury) , staphylococcus aureus , antimicrobial , microbiology and biotechnology , homology (biology) , chemistry , bacteria , escherichia coli , peptide , antibiotics , biology , amino acid , lactic acid , biochemistry , genetics , anatomy , lactobacillus plantarum , gene
Bacteriocins are bacterial proteins or peptides exhibiting antimicrobial activity and synthesized on ribosomes. For a high molecular weight bacteriocin produced by the Limosilactobacillus fermentum IIE MD-150 strain and having the GRAS status (Generally Recognized as Safe), an amino acid sequence homology with enterolysin A produced by the Enterococus faecalis LMG 2333 strain was found. Lactobacillus fermentum IIE MD-150 can be used in the prevention and complex treatment of infectious diseases caused by antibiotic-resistant strains of Staphylococcus aureus.