Open AccessS-Protein of the Probiotic Strain Lactobacillus crispatus 2029 Prevents the Growth of Permeability of the Caco-2 Monolayer of Human Enterocytes Induced by Intestinal Infections
Author(s) -
Igor V. Kosarev,
Raisa N. Vasilenko,
Vyacheslav M. Abramov,
Vadim K. Sakulin,
В. С. Хлебников,
S. Yu. Pchelintsev,
А. В. Мачулин,
Т. Н. Абашина,
Vladimir A. Samoilenko,
Vladimir N. Uversky,
Andrey V. Karlyshev
Publication year - 2021
Publication title -
biomedicina
Language(s) - English
Resource type - Journals
eISSN - 2713-0428
pISSN - 2074-5982
DOI - 10.33647/2074-5982-17-3-79-83
Subject(s) - probiotic , caco 2 , microbiology and biotechnology , intestinal permeability , strain (injury) , chemistry , biology , bacteria , in vitro , biochemistry , immunology , anatomy , genetics
The use of a biomodel of the confluent monolayer Caco-2 of enterocytes allowed us to reveal the ability of the S-protein isolated from strain LC2029 to prevent permeability disorders resulting from intestinal infections induced by pathogens (E. coli O157: H7, C. jejuni ATCC 33291, S. enteritidis ATCC 25928). This is important for maintaining the efficiency of the intestinal barrier.