Open AccessEffect of Chitosan, Photomodulation and Physical Exercises on the Regeneration of Operating Wounds in Experiment
Author(s) -
Tynchtynbek Bakytbekovich Uzakov,
O. Uzakov,
G. Belov,
E. Baibulatov
Publication year - 2021
Publication title -
bûlletenʹ nauki i praktiki
Language(s) - English
Resource type - Journals
ISSN - 2414-2948
DOI - 10.33619/2414-2948/71/21
Subject(s) - photostimulation , medicine , wound healing , surgery , abdominal wall , chitosan , chemistry , biochemistry
The study was carried out on 60 white Wistar rats, simulating a surgical wound. The rats were divided into 5 groups of 10 rats each. Group 1 — control, rats from this group made an incision on the side wall, abdominal wall, followed by natural healing within 10 days; Group 2 — an incision followed by the use of chitosan ointment; Group 3 — the wound was exposed to photostimulation treated with methylene blue; Group 4 — physical activity in the postoperative period on a treadmill for 30 minutes; Group 5 — complex application of chitosan, photostimulation and physical activity. Wound healing was recorded by determining the area, photo-fixation of the wound was performed, and histological examinations of the skin and internal organs were performed. Obtained results: The best wound healing according to planimetry and histological studies was reliably noted in group 5 with the complex treatment of the surgical wound. Conclusions: The rehabilitation complex for large surgical wounds should include previously local effects of physiotherapeutic procedures and physical activity.