Open AccessBiological features of SARS-CoV-2 and current approaches to antiviral therapy and vaccination
Author(s) -
Snježana Židovec Lepej,
Petra Korać,
Dijana Škorić,
Margarita Batović,
Paula Gršković,
Valerija Begić,
Suzana Harabajsa,
Leona Radmanić,
Petra Šimičić
Publication year - 2020
Publication title -
molecular and experimental biology in medicine
Language(s) - English
Resource type - Journals
ISSN - 2584-671X
DOI - 10.33602/mebm.3.2.1
Subject(s) - pandemic , covid-19 , vaccination , pneumonia , identification (biology) , antiviral therapy , virology , medicine , intensive care medicine , immunology , biology , virus , infectious disease (medical specialty) , outbreak , disease , pathology , chronic hepatitis , botany
Since the first description of patients with pneumonia of unknown origin in Wuhan in December 2019, unprecedented efforts of the international scientific community led tothe identification and molecular characterization of its etiological agent,e.g. SARS-CoV-2. The global pandemic of COVID-19 represents an outstandingchallenge for the scientists and medical professionals worldwide. In thisreview, we discuss the most important aspects of SARS-CoV-2 biology andvirology including antiviral and immunomodulatory treatment strategies as wellas vaccine development.