Open AccessZNF281 Regulates Cell Proliferation, Migration and Invasion in Colorectal Cancer through Wnt/β-Catenin Signaling
Author(s) -
Changjiang Qin,
Pei-Long Bu,
Qi Zhang,
Jiangtao Chen,
Quanying Li,
Jiantao Liu,
Hai-Chang Dong,
Xuequn Ren
Publication year - 2019
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.33594/000000104
Subject(s) - wnt signaling pathway , colorectal cancer , cancer research , gene knockdown , metastasis , oncogene , cell growth , biology , catenin , cell migration , cell , blot , cancer , signal transduction , medicine , cell culture , cell cycle , microbiology and biotechnology , gene , genetics
Zinc Finger Protein 281 (ZNF281) was recently identified as a novel oncogene in several human carcinomas. However, the clinical significance of ZNF281 in colorectal cancer (CRC) and the molecular mechanisms by which ZNF281 promotes the growth and metastasis of CRC remain unknown.