Open AccessThe investigation of adaptogenic and hepatoprotective properties of Ilex paraguariensis on experimental models in vivo
Author(s) -
Aksana I. Hubich,
Svyatlana S. Okarakava,
Darya V. Kopyleva,
Nadezhda S. Jaafar,
Dziyana V. Duts,
Maryia I. Koval
Publication year - 2021
Publication title -
žurnal belorusskogo gosudarstvennogo universiteta. bilologiâ/žurnal belorusskogo gosudarstvennogo universiteta. biologiâ
Language(s) - English
Resource type - Journals
eISSN - 2617-3964
pISSN - 2521-1722
DOI - 10.33581/2521-1722-2021-2-43-51
Subject(s) - caffeine , silybum marianum , antioxidant , lipid peroxidation , decoction , chemistry , in vivo , pharmacology , liver injury , traditional medicine , biochemistry , medicine , biology , endocrinology , microbiology and biotechnology
This work is devoted to the study of the effect of Ilex paraguariensis decoction for energy and carbohydrate metabolism in conditions of increased physical activity, the analysis of the stabilisation possibilities of liver injury and lipid peroxidation markers in rats in an experimental model of chronic alcohol intoxication. It’s established that I. paraguariensis exhibits antioxidant and hepatoprotective effects in rats with experimental alcoholic liver, comparable to the action of classical plant hepatoprotector – Silybum marianum, has a stimulating and adaptogenic effects in experimental model of physical activity, comparable to the energy drink «Wild Jaguar». The results obtained may be due to the presence of flavonoids, ascorbic and chlorogenic acids, exhibiting an antioxidant effect, as well as caffeine, which is known to stimulate the work of the central nervous and cardiovascular systems.