Open AccessExperimental eva luation of the protective properties of the original chewing compositions in relation to the toxic effect of water soluble nicotos-containing substances of the tobacco on an immature organism
Author(s) -
Анна Валерьевна Адамович,
Виталий Васильевич Шевляков,
Т. М. Юрага
Publication year - 2019
Publication title -
žurnal belorusskogo gosudarstvennogo universiteta. bilologiâ/žurnal belorusskogo gosudarstvennogo universiteta. biologiâ
Language(s) - English
Resource type - Journals
eISSN - 2617-3964
pISSN - 2521-1722
DOI - 10.33581/2521-1722-2019-1-13-24
Subject(s) - computer science
On the experimental model of subchronic oral alkaloidization of immature white rats with their 59-daily consumption of aqueous extract from tobacco products in cyclically increasing concentrations of the total alkaloids, the potential protective properties of the developed original prophylactic chewable compositions (based on mexidol, glycine, vitamin complex and phytocomponents) in relation to toxic effect of the complex of soluble substances of tobacco were studied. The results of the study testify to the protective effect of prophylactic chewable compositions with their 2-week consumption of alkaloidized animals on models of continuing consumption of aqueous extract from tobacco products and its termination, which was reflected in the normalization or significant improvement of morphofunctional indicators of the organism of intoxication genesis in alkaloidized animals. The developed formulations of prophylactic chewable compositions are promising for drug support in the prevention and cessation of tobacco use by young people and are recommended for further study for this purpose.