Open AccessVery early EEG responses to a meaningful auditory stimulus in the frontal lobes: an intracerebral study in humans
Author(s) -
Miloslav Kukleta,
B. Turak,
J. Louvel
Publication year - 2010
Publication title -
physiological research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.647
H-Index - 70
eISSN - 1802-9973
pISSN - 0862-8408
DOI - 10.33549/physiolres.931831
Subject(s) - stimulus (psychology) , audiology , precentral gyrus , neuroscience , psychology , electroencephalography , gyrus , auditory stimuli , evoked potential , frontal lobe , medicine , cognitive psychology , magnetic resonance imaging , perception , radiology
Frontal auditory evoked potentials (FAEPs) obtained as aresponse to the warning auditory stimulus of a contingentnegative variation task from depth electrodes were investigated.The second, imperative stimulus was visual. Thirteen epilepticpatients participated in the study. Records from 20 electrodes of10 patients exhibited signs of local generation. They werelocalized in the motor cortices (7 cases), in the superior, medial,and inferior frontal gyri (7 cases), in the cingulate gyrus (5cases), and in the nucleus caudatus (1 case). A typical FAEP fromthese generators consisted of three components: (i) first negativewave peaking at 99±13 ms; (ii) positive wave peaking at 181±21ms; (iii) second negative wave peaking at 324±63 ms. In 11generators no evoked activity to visual stimulus was observed; inthe remaining 9 generators both auditory and visual stimulievoked a response. FAEPs with very early onsets (onset latencybelow 20 ms) were found in three sites in the precentral gyrus.