Open AccessCatheter-based management of aortic valve regurgitation in experimental cardiology
Author(s) -
J Šochman,
Peregrin Jh
Publication year - 2008
Publication title -
physiological research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.647
H-Index - 70
eISSN - 1802-9973
pISSN - 0862-8408
DOI - 10.33549/physiolres.931223
Subject(s) - medicine , clinical practice , intensive care medicine , regurgitation (circulation) , cardiology , aortic valve , catheter , surgery , family medicine
Non-surgical management of aortic valve disease has been givenconsiderable attention. Several recent publications have alreadyreported its use in clinical practice. The main issue is to get anunderstanding of the pathophysiological processes and, mostimportantly, extensive experimental activity. In addition to testingvarious animal models, technical and material aspects are alsobeing intensively investigated. It is not clear yet whether thedurability and applicability of this promising development will becomparable with the standard of current cardiac surgery.Nonetheless, even the use of some models as a temporaryapproach helping to improve the circulatory status, not allowingsafe surgery, is certainly justified. At any rate, a new stage ofresearch and clinical application has been set off. However,experimental background continues to be simply indispensable.The paper is a short review of the issue.