Open AccessQuo vadis porphyrin chemistry?
Author(s) -
Král,
Jarmila Králová,
Robert Kaplánek,
Tomáš Břı́za,
Pavel Martásek
Publication year - 2006
Publication title -
physiological research
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.647
H-Index - 70
eISSN - 1802-9973
pISSN - 0862-8408
DOI - 10.33549/physiolres.930000.55.s2.3
Subject(s) - porphyrin , chemistry , photodynamic therapy , heme , combinatorial chemistry , nanotechnology , photochemistry , organic chemistry , materials science , enzyme
This review summarizes recent developments in the area of porphyrin chemistry in the direction of biological applications. Novel synthetic methodologies are reviewed for porphyrin synthesis, porphyrin analog synthesis, stable porphyrinogens -- calixpyrroles, expanded porphyrins. Unique biological properties of those compounds are desribed with focus on photodynamic therapy (PDT) and molecular recognition properties. Special attentions given to metalloporphyrins with potential to affect heme degradation and CO formation.