Open AccessTHE EFFECT OF EGGPLANT JUICE TO THE THICKNESS OF AORTIC WALL IN WHITE RAT
Author(s) -
ira Dwijayanti
Publication year - 2021
Publication title -
jurnal teknologi pangan dan gizi (jurnal of food technology and nutrition)/jurnal teknologi pangan dan gizi
Language(s) - English
Resource type - Journals
eISSN - 2613-909X
pISSN - 1411-7096
DOI - 10.33508/jtpg.v20i2.3174
Subject(s) - anthocyanin , aorta , thickening , analysis of variance , food science , fruit juice , chemistry , lipid peroxidation , zoology , medicine , biology , biochemistry , surgery , oxidative stress , polymer science
Atherosclerosis is a complex chronic disease characterized by the accumulation of lipids within arterial walls. Delphinidin-3-(p-coumaroylrutinoside)-5-glucoside (nasunin), an anthocyanin, was isolated as purple-colored crystals from eggplant peels. Nasunin protection against induced lipid peroxidation in rat. The aim of study was to determine the effect of eggplant juice to the thickness of aortic wall of white rat with atherogenic diet. This true experimental laboratoric study using control group post test design performed in white rat that placed in pharmacologic laboratory of Brawijaya University. Sampling was carried out by completely random sampling with 25 rats for the total sample. Data were processed and analyzed using SPSS 16. Statistical test using one-way ANOVA and continuing with post hoc Tukey. The result showed there was a significant effect between positive control of diet atherogenic with the dosage I (1,3 gr/3 ml), dosage II (2,6 gr/3 ml), and dosage III (5,2 gr/3 ml) of eggplant juice to aorta wall thickness (p=0,000;p<0,05) . We can conclude that the effective dosage of eggplant juice for reducing the progression of aortic wall thickening is dosage III (5,2 gr/3 ml).