Open AccessCharacterization of Ferric Chloride-Induced Arterial Thrombosis Model of Mice and the Role of Red Blood Cells in Thrombosis Acceleration
Author(s) -
Yeseul Shim,
Il Kwon,
Youngseon Park,
Heow Won Lee,
Jayoung Kim,
Young Dae Kim,
Hyo Suk Nam,
Sungha Park,
Ji Hoe Heo
Publication year - 2021
Publication title -
yonsei medical journal/yonsei medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.702
H-Index - 63
eISSN - 1976-2437
pISSN - 0513-5796
DOI - 10.3349/ymj.2021.62.11.1032
Subject(s) - thrombus , platelet , thrombosis , fibrin , ferric , chemistry , platelet activation , pathology , medicine , biophysics , immunology , biology , inorganic chemistry
The ferric chloride (FeCl 3 )-induced thrombosis model is widely used for thrombosis research. However, it lacks standardization with uncertainty in the exact mechanism of thrombosis. This study aimed to characterize thrombus formation in a mouse model.