Open AccessIslet Transplantation and Regeneration for Treatment of Diabetes
Author(s) -
Yoshio Yamada
Publication year - 2004
Publication title -
yonsei medical journal/yonsei medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.702
H-Index - 63
eISSN - 1976-2437
pISSN - 0513-5796
DOI - 10.3349/ymj.2004.45.suppl.53
Subject(s) - islet , transplantation , medicine , diabetes mellitus , regeneration (biology) , endocrinology , biology , microbiology and biotechnology
Islet transplantation has the potential to restore normoglycemia and prevent the development of diabetic complications such as retinopathy, nephropathy and neuropathy, and could therefore ve a valuable treatment for diabetic patients. The scarcity of available islets is an obstacle for clinically successful islet transplantation. To resolve the problems, we have examined the two methods, islet transplantation with extracellular matrix and in vivo expansion of islets with electrically-transfection of growth factors.