Complete Resolution of Posttransplant Lymphoproliferative Disorder (Diffuse Large B-cell Lymphoma) with Reduction of Immunosuppressive Therapy | Zendy

Han Jak Ryu | Zendy; Jee Sook Hahn | Zendy; Yu Seun Kim | Zendy; Kiil Park | Zendy; Woo Ick Yang | Zendy; Jong Doo Lee | Zendy

Open Access

Complete Resolution of Posttransplant Lymphoproliferative Disorder (Diffuse Large B-cell Lymphoma) with Reduction of Immunosuppressive Therapy

Author(s) -

Han Jak Ryu,

Jee Sook Hahn,

Yu Seun Kim,

Kiil Park,

Woo Ick Yang,

Jong Doo Lee

Publication year - 2004

Publication title -

yonsei medical journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.702

H-Index - 63

eISSN - 1976-2437

pISSN - 0513-5796

DOI - 10.3349/ymj.2004.45.3.527

Subject(s) - immunosuppression , lymphoproliferative disorders , lymphoma , post transplant lymphoproliferative disorder , medicine , transplantation , immunology , diffuse large b cell lymphoma , organ transplantation , pathology , rituximab

Posttransplant lymphoproliferative disorder (PTLD) is a serious complication of organ transplantation. PTLD is the disorder arising from the combined effects of Epstein-Barr virus associated lymphoid proliferation with the disruption of the normal immune control by the cytotoxic T cells. The treatment for PTLD is one of the most controversial topics in solid organ transplantation. It is well known that the initial management of PTLD is a reduction of immunosuppression. Early diagnosis and the early reduction in immunosuppression are essential even for monomorphic lymphoma. We report here on a case of the complete resolution of PTLD (diffuse large B cell lymphoma) which occurred after a drastic reduction of immunosuppression in a renal transplant recipient.

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