Open AccessGraves' Disease Associated with Klinefelter's Syndrome
Author(s) -
Jong Suk Park,
Chul Sik Kim,
Joo Young Nam,
Dol Mi Kim,
Soo Jee Yoon,
Chul Woo Ahn,
Bong Soo,
Sung Kil Lim,
Kyung Rae Kim,
Hyun Chul Lee,
Kap Bum Huh
Publication year - 2004
Publication title -
yonsei medical journal/yonsei medical journal
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.702
H-Index - 63
eISSN - 1976-2437
pISSN - 0513-5796
DOI - 10.3349/ymj.2004.45.2.341
Subject(s) - klinefelter syndrome , gynecomastia , azoospermia , medicine , graves' disease , infertility , endocrinology , male infertility , testosterone (patch) , disease , pediatrics , gynecology , biology , genetics , pregnancy
Klinefelter's syndrome is one of the most common forms of primary hypogonadism and infertility in males. It is characterized by small and firm testes, gynecomastia, azoospermia, and an elevated gonadotropin level. The frequencies of diabetes mellitus, breast cancer, and germ cell neoplasia increases in Klinefelter's syndrome. We report upon a 35 year-old male patient with Graves' disease in association with Klinefelter's syndrome; as confirmed by chromosome analysis. The patient is being treated with antithyroid medication for Graves' disease and by testosterone replacement for Klinefelter's syndrome.