Open AccessThe Application of Human Papillomavirus Testing to Cervical Cancer Screening
Author(s) -
Hyo Pyo Lee,
Sang Soo Seo
Publication year - 2002
Publication title -
yonsei medical journal/yonsei medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.702
H-Index - 63
eISSN - 1976-2437
pISSN - 0513-5796
DOI - 10.3349/ymj.2002.43.6.763
Subject(s) - medicine , cervical cancer , human papillomavirus , cervical cancer screening , cytology , cancer , incidence (geometry) , oncology , cancer screening , gynecology , papillomaviridae , screening test , pathology , pediatrics , physics , optics
Although cytologic screening has considerably reduced the incidence of cervical cancer, there are some problems which remain to be solved, such as the low sensitivity of this procedure. HPV testing is fundamentally different from conventional cytologic testing, because it evaluates the HPV infection itself, the most important causative factor for cervical cancer. In this study, the roles and clinical applications of HPV testing in cervical cancer screening are examined from 3 standpoints: in primary screening, in the management of women with low-grade cytologic abnormalities, and in the follow-up after treatment of pre-invasive or early invasive lesions.