Open AccessIslet cell hyperplasia of the pancreas presenting as hyperinsulinemic hypoglycemia in an adult
Author(s) -
Youn Wha Kim,
Yong Koo Park,
Jae Hoon Park,
Sang Mok Lee,
Juhie Lee,
Suk Whan Ko,
Moon Ho Yang
Publication year - 2000
Publication title -
yonsei medical journal/yonsei medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.702
H-Index - 63
eISSN - 1976-2437
pISSN - 0513-5796
DOI - 10.3349/ymj.2000.41.3.426
Subject(s) - nesidioblastosis , hyperinsulinemic hypoglycemia , medicine , pancreas , hypoglycemia , pancreatectomy , endocrine system , insulinoma , islet , hyperplasia , hyperinsulinism , percutaneous , gastroenterology , insulin , hormone , insulin resistance
A 72-year-old man who had suffered several episodes of syncope was diagnosed as having hyperinsulinemic hypoglycemia. Although imaging studies and percutaneous transhepatic portal venous sampling did not reveal the existence of any tumors in the pancreas, distal pancreatectomy was performed because the possibility of a small pancreatic endocrine tumor could not be completely rejected. External examination of the surgically removed pancreas did not reveal any tumors. Microscopically, the pancreas exhibited diffuse islet cell hyperplasia without nesidioblastosis. The patient remains euglycemic and has tolerated 24-hour fasting without any medication for a period of 10 months after the operation.