Assignments of the tyrosinase related protein-1 and -2 genes to human chromosome bands 9p23 and 13q32.1 byin situhybridization | Zendy

Young Mi Lee | Zendy; Mahn Joon Ha | Zendy; Min Sook Ryu | Zendy; Eunpyo Moon | Zendy; Sungbin Im | Zendy; Hyon Ju Kim | Zendy; Wankee Kim | Zendy

Open Access

Assignments of the tyrosinase related protein-1 and -2 genes to human chromosome bands 9p23 and 13q32.1 byin situhybridization

Author(s) -

Young Mi Lee,

Mahn Joon Ha,

Min Sook Ryu,

Eunpyo Moon,

Sungbin Im,

Hyon Ju Kim,

Wankee Kim

Publication year - 2000

Publication title -

yonsei medical journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.702

H-Index - 63

eISSN - 1976-2437

pISSN - 0513-5796

DOI - 10.3349/ymj.2000.41.3.398

Subject(s) - gene , fluorescence in situ hybridization , microbiology and biotechnology , biology , chromosome , genetics , gene mapping , bacterial artificial chromosome , in situ , chemistry , genome , organic chemistry

To determine the precise chromosomal localization of tyrosine related protein-1 and -2 (TRP-1 and TRP-2) genes by fluorescence in situ hybridization, we used DNAs isolated from human bacterial artificial chromosome clones. They contain genomic sequences with approximately 120 kb inserts for TRP-1 and TRP-2. The TRP-1 and TRP-2 genes were assigned to human chromosome bands 9p23 and 13q32.1, respectively. These results confirmed the previously mapped location for the TRP-1 gene and more precisely located the TRP-2 gene, which had previously been mapped to chromosome 13q31-q32.

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