
Antimicrobial resistance patterns ofBacteroides fragilisgroup organisms in Korea
Author(s) -
Kyungwon Lee,
Hee Bong Shin,
Yunsop Chong
Publication year - 1998
Publication title -
yonsei medical journal/yonsei medical journal
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.702
H-Index - 63
eISSN - 1976-2437
pISSN - 0513-5796
DOI - 10.3349/ymj.1998.39.6.578
Subject(s) - bacteroides fragilis , cefoxitin , microbiology and biotechnology , piperacillin , antimicrobial , imipenem , clindamycin , cefotaxime , metronidazole , antibiotics , biology , antibiotic resistance , bacteria , pseudomonas aeruginosa , staphylococcus aureus , genetics
Antimicrobial resistance patterns of 913 clinical isolates of Bacteroides fragilis group organisms were monitored during an 8-year period in Korea. In general the resistance rates of the non-fragilis B. fragilis group species were higher than those of B. fragilis for all the drugs tested. The rate of resistance to clindamycin remarkably increased and those to some beta-lactam drugs such as piperacillin and cefotaxime also increased. No isolates were found to be resistant to imipenem, metronidazole, or chloramphenicol. beta-lactam and beta-lactamase inhibitor combinations and cefoxitin were more active than the other beta-lactams. Therefore, these agents may be considered when empirical selection of antimicrobial agents is required to treat severe anaerobic infections.